Zyloprim (Allopurinol)

Zyloprim limits the production of xanthine oxidase, a substance that produces uric acid in the body. It is prescribed for preventing gout, kidney stones, and kidney damage caused by uric acid.

Zyloprim 300 mg (Normal Dosage)

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Zyloprim 100 mg (Low Dosage)

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How it works

Zyloprim limits the production of xanthine oxidase, a substance that produces uric acid in the body.

Guidelines for usage

Follow the dosage instructions provided by your doctor or as mentioned in the instruction booklet/product label.

The recommended doses range from 100 mg to 800 mg daily depending on the severity of the condition.

Always use only as prescribed. Never exceed the dosage.

Zyloprim may be used with or without food.

Doctors recommend that you swallow the whole tablet/capsules with a glass of water unless it is specified that it can be broken or chewed.

NOTE: Use only if prescribed to you and intended for your use. Do not share with others.

Missed Dose

It is common for people to forget their dosage times and miss doses.

Do not panic if you have missed a dose.

Instead, skip the missed dose and take your next dose at the scheduled time. Do not double up or take more than what the doctor has prescribed.

How & where do I store Zyloprim?

The medicine label contains detailed instructions regarding safe storage of the medication. Most medicines are best stored at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Some medications may require to be refrigerated. Please check the product label.

Keep it away from the reach of children. Ensure that it is not exposed to direct sunlight or moisture.

Ask your pharmacist about disposing off excessive medication that is past expiry date.

Overdose Related Information

If you accidentally consume more medication than what was prescribed, then contact an emergency healthcare center immediately.
Safety Information/ Warning Precautions

Discuss your medical history with your healthcare provider before you start using any new medication.

Ensure that you mention the following:

Any prior serious ailment, lifestyle disease or surgery
All the prescription drugs, OTC health supplements, herbal supplements that you are using currently
Your alcohol intake and whether you smoke or not
Any history of a known allergic reaction to prescription drugs or food
You have kidney or liver disease, heart problems (eg, congestive heart failure), bone marrow problems, high blood pressure, or diabetes.

This will allow your healthcare provider to prescribe the apt dosage of the medication for you.

To be avoided

You must avoid using Zyloprim if it you are allergic to any ingredient in it or if:

Patient is a child (except if taking it because of high levels of uric acid caused by cancer)
Patient is a nursing mother (except if taking it because of high levels of uric acid caused by cancer)

Using Alcohol

Zyloprim is known to cause drowsiness or dizziness. Your vision may be blurred and your judgement affected if you consume alcohol with this medication. So, avoid using alcohol while using Zyloprim.

These effects may also get aggravated due to hot weather or fever or severe exercise. So, be cautious when you stand up after a long time from a sitting or lying position. If you feel giddy then lie down immediately and seek medical help.

Possible Drug & Food Interactions

Certain prescription drugs or health supplements or even food items are known to interact with the effects of medications. Zyloprim is known to have possible interactions with the following medications.

Amoxicillin or ampicillin, Chlorpropamid
Dicumarol or oral anticoagulants (eg, warfarin)
Thiazide diuretics (eg, hydrochlorothiazide) or uricosurics (eg, probenecid),
Cyclosporine or thiopurines (eg, azathioprine, mercaptopurine)

Additional Information

If your doctor has prescribed laboratory tests then ensure that you do not miss out on them.

Important Information for Pregnant Women

Zyloprim is categorized under FDA category which indicates that it is safe to be used by pregnant women.

Discuss the potential risks with your healthcare provider before using the medication.

Certain medications may be found in breast milk so speak to your child’s doctor to rule out any possibilities of risk.
Side Effects

Report the following side effects to your doctor only if they become bothersome or do not stop on their own:


The following side effects require immediate medical attention. So report these to your doctor immediately.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue)

Blood in urine or painful urination; dark urine; fever, chills, or sore throat; irritation of the eyes; joint pain; loss of appetite

red, swollen, blistered, or peeling skin

stomach pain; unexplained weight loss; unusual bruising or bleeding; unusual muscle pain or weakness; yellowing of the skin or eyes.

Black tarry stools